Instituut voor Neuropathische Pijn
English articles Burning mouth syndrome (BMS), burning lip and tongue
| Burning mouth syndrome (BMS), burning lip and tongue |
Burning mouth syndrome (BMS), burning lip and burning tongue. Very unpleasant. Penza and colleagues from the *Neuromuscular Diseases Unit, IRCCS Foundation "Carlo Besta" National Neurological Institute, University of Brescia, in Italy interviewed more than 50 patients and correlated the symptoms with the results of a tongue biopsy.
Burning Mouth Syndrome and biopsiesA tongue biopsy with the quantification of epithelial nerve fibers (ENF) was performed in 51 patients. The results: Compared with 9 healthy participants, epithelial innervation density was significantly reduced in 38 patients and normal in 13 patients. Patients with reduced ENF density complained of pain in the whole tongue, lips, hard palate, and alveolar ridges, reported dysgeusia and xerostomia in 29% of cases. Patients with normal innervation complained of pain on the tip of the tongue, reported dysgeusia and xerostomia in 7.7% of cases. The conclusion was: Our study shows that BMS can present with two distinct clinical pictures and that tongue biopsy can contribute to the assessment of the diagnosis.[1] Jan M. Keppel Hesselink, MD, PhD, july 2010 Referenties[1]: Penza P, Majorana A, Lombardi R, Camozzi F, Bonadeo S, Sapelli P, Lauria G. | "Burning tongue" and "burning tip": the diagnostic challenge of the burning mouth syndrome. | Clin J Pain. | 2010 Jul-Aug;26(6):528-32. |